4AP6
Crystal structure of human POFUT2 E54A mutant in complex with GDP- fucose
Summary for 4AP6
Entry DOI | 10.2210/pdb4ap6/pdb |
Related | 4AP5 |
Descriptor | GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | transferase, gt-b, gt68 |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Endoplasmic reticulum (By similarity): Q9Y2G5 |
Total number of polymer chains | 4 |
Total formula weight | 202042.27 |
Authors | Chen, C.,Keusch, J.J.,Klein, D.,Hess, D.,Hofsteenge, J.,Gut, H. (deposition date: 2012-03-30, release date: 2012-08-08, Last modification date: 2020-07-29) |
Primary citation | Chen, C.I.,Keusch, J.J.,Klein, D.,Hess, D.,Hofsteenge, J.,Gut, H. Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation. Embo J., 31:3183-, 2012 Cited by PubMed: 22588082DOI: 10.1038/EMBOJ.2012.143 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.401 Å) |
Structure validation
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