4AP2
Crystal structure of the human KLHL11-Cul3 complex at 2.8A resolution
Summary for 4AP2
Entry DOI | 10.2210/pdb4ap2/pdb |
Descriptor | KELCH-LIKE PROTEIN 11, CULLIN-3, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | ubiquitination, e3 ligase, cell cycle |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus: Q13618 |
Total number of polymer chains | 2 |
Total formula weight | 83130.71 |
Authors | Canning, P.,Cooper, C.D.O.,Krojer, T.,Filippakopoulos, P.,Ayinampudi, V.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Bullock, A.N.,Structural Genomics Consortium (SGC) (deposition date: 2012-03-30, release date: 2012-05-09, Last modification date: 2024-05-08) |
Primary citation | Canning, P.,Cooper, C.D.O.,Krojer, T.,Murray, J.W.,Pike, A.C.W.,Chaikuad, A.,Keates, T.,Thangaratnarajah, C.,Hojzan, V.,Marsden, B.D.,Gileadi, O.,Knapp, S.,von Delft, F.,Bullock, A.N. Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases. J.Biol.Chem., 288:7803-, 2013 Cited by PubMed: 23349464DOI: 10.1074/JBC.M112.437996 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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