4AP2

Crystal structure of the human KLHL11-Cul3 complex at 2.8A resolution

Summary for 4AP2

Entry DOI	10.2210/pdb4ap2/pdb
Descriptor	KELCH-LIKE PROTEIN 11, CULLIN-3, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywords	ubiquitination, e3 ligase, cell cycle
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Nucleus: Q13618
Total number of polymer chains	2
Total formula weight	83130.71
Authors	Canning, P.,Cooper, C.D.O.,Krojer, T.,Filippakopoulos, P.,Ayinampudi, V.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Bullock, A.N.,Structural Genomics Consortium (SGC) (deposition date: 2012-03-30, release date: 2012-05-09, Last modification date: 2018-01-24)
Primary citation	Canning, P.,Cooper, C.D.O.,Krojer, T.,Murray, J.W.,Pike, A.C.W.,Chaikuad, A.,Keates, T.,Thangaratnarajah, C.,Hojzan, V.,Marsden, B.D.,Gileadi, O.,Knapp, S.,von Delft, F.,Bullock, A.N. Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases. J.Biol.Chem., 288:7803-, 2013 Cited by PubMed: 23349464 DOI: 10.1074/JBC.M112.437996 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation