4AOV
DpIDH-NADP. The complex structures of Isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila, support a new active site locking mechanism
Summary for 4AOV
Entry DOI | 10.2210/pdb4aov/pdb |
Related | 2UXQ 2UXR 4AOU |
Descriptor | ISOCITRATE DEHYDROGENASE [NADP], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ISOCITRIC ACID, ... (5 entities in total) |
Functional Keywords | oxidoreductase, temperature adaptation, thermophilic, psychrophilic, nadp+ selectivity, domain movements |
Biological source | DESULFOTALEA PSYCHROPHILA |
Total number of polymer chains | 1 |
Total formula weight | 46608.96 |
Authors | Leiros, H.-K.S.,Fedoy, A.-E.,Leiros, I.,Steen, I.H. (deposition date: 2012-03-30, release date: 2012-07-11, Last modification date: 2024-05-08) |
Primary citation | Leiros, H.-K.S.,Fedoy, A.-E.,Leiros, I.,Steen, I.H. The Complex Structures of Isocitrate Dehydrogenase from Clostridium Thermocellum and Desulfotalea Psychrophila Suggest a New Active Site Locking Mechanism FEBS Open Bio., 2:159-, 2012 Cited by PubMed: 23650595DOI: 10.1016/J.FOB.2012.06.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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