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4AOV

DpIDH-NADP. The complex structures of Isocitrate dehydrogenase from Clostridium thermocellum and Desulfotalea psychrophila, support a new active site locking mechanism

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ISOCITRATE DEHYDROGENASE [NADP]polymer40245649.11UniProt (Q6AQ66)
Pfam (PF00180)
DESULFOTALEA PSYCHROPHILA
2B
(A)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
3C
(A)
ISOCITRIC ACIDnon-polymer192.11Chemie (ICT)
4D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5E
(A)
waterwater18.0227Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight45649.1
Non-Polymers*Number of molecules3
Total formula weight959.8
All*Total formula weight46609.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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