Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0006102 | biological_process | isocitrate metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE NAP A 1403 |
| Chain | Residue |
| A | ALA73 |
| A | HIS305 |
| A | GLY306 |
| A | THR307 |
| A | VAL308 |
| A | ARG310 |
| A | HIS311 |
| A | THR323 |
| A | ASN324 |
| A | ICT1404 |
| A | HOH2042 |
| A | THR74 |
| A | HOH2045 |
| A | HOH2115 |
| A | HOH2141 |
| A | HOH2143 |
| A | HOH2163 |
| A | HOH2164 |
| A | HOH2165 |
| A | HOH2166 |
| A | HOH2178 |
| A | HOH2190 |
| A | THR76 |
| A | HOH2192 |
| A | HOH2199 |
| A | HOH2225 |
| A | HOH2226 |
| A | HOH2227 |
| A | ARG81 |
| A | ASN95 |
| A | ASP250 |
| A | ARG254 |
| A | LEU285 |
| A | ALA286 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ICT A 1404 |
| Chain | Residue |
| A | THR76 |
| A | SER93 |
| A | ASN95 |
| A | ARG99 |
| A | ARG108 |
| A | ARG131 |
| A | TYR138 |
| A | LYS209 |
| A | ILE212 |
| A | ASP249 |
| A | ASP272 |
| A | ALA304 |
| A | NAP1403 |
| A | MG1405 |
| A | HOH2067 |
| A | HOH2141 |
| A | HOH2143 |
| A | HOH2177 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1405 |
| Chain | Residue |
| A | ASP249 |
| A | ASP272 |
| A | ICT1404 |
| A | HOH2067 |
| A | HOH2177 |
Functional Information from PROSITE/UniProt
| site_id | PS00470 |
| Number of Residues | 20 |
| Details | IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NYDGDVmSDmvAsaf.GSLAM |
| Chain | Residue | Details |
| A | ASN268-MET287 | |
