4AD7

Crystal structure of full-length N-glycosylated human glypican-1

Summary for 4AD7

• Entry DOI: 10.2210/pdb4ad7/pdb
• Related: 4ACR
• Descriptor: GLYPICAN-1, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: membrane protein, proteoglycan, glycosaminoglycans, heparan sulfate, helical bundle, glycoprotein, sugar binding protein
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted glypican-1: Secreted, extracellular space: P35052
• Total number of polymer chains: 4
• Total formula weight: 236468.26

Authors

Svensson, G.,Awad, W.,Mani, K.,Logan, D.T. (deposition date: 2011-12-22, release date: 2012-03-21, Last modification date: 2023-12-20)

• Primary citation: Svensson, G.,Awad, W.,Hakansson, M.,Mani, K.,Logan, D.T.; Crystal Structure of N-Glycosylated Human Glypican-1 Core Protein: Structure of Two Loops Evolutionarily Conserved in Vertebrate Glypican-1.; J.Biol.Chem., 287:14040-, 2012; PubMed: 22351761; DOI: 10.1074/JBC.M111.322487

Experimental method

X-RAY DIFFRACTION (2.945 Å)