4AD7

Crystal structure of full-length N-glycosylated human glypican-1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005654	cellular_component	nucleoplasm
A	0005768	cellular_component	endosome
A	0005796	cellular_component	Golgi lumen
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0009966	biological_process	regulation of signal transduction
A	0009986	cellular_component	cell surface
A	0014037	biological_process	Schwann cell differentiation
A	0016477	biological_process	cell migration
A	0017134	molecular_function	fibroblast growth factor binding
A	0030200	biological_process	heparan sulfate proteoglycan catabolic process
A	0031012	cellular_component	extracellular matrix
A	0032288	biological_process	myelin assembly
A	0040037	biological_process	negative regulation of fibroblast growth factor receptor signaling pathway
A	0043202	cellular_component	lysosomal lumen
A	0043236	molecular_function	laminin binding
A	0045121	cellular_component	membrane raft
A	0045202	cellular_component	synapse
A	0062023	cellular_component	obsolete collagen-containing extracellular matrix
A	0070062	cellular_component	extracellular exosome
A	0098552	cellular_component	side of membrane
A	1905475	biological_process	regulation of protein localization to membrane
A	2001016	biological_process	positive regulation of skeletal muscle cell differentiation
B	0005507	molecular_function	copper ion binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005654	cellular_component	nucleoplasm
B	0005768	cellular_component	endosome
B	0005796	cellular_component	Golgi lumen
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0009966	biological_process	regulation of signal transduction
B	0009986	cellular_component	cell surface
B	0014037	biological_process	Schwann cell differentiation
B	0016477	biological_process	cell migration
B	0017134	molecular_function	fibroblast growth factor binding
B	0030200	biological_process	heparan sulfate proteoglycan catabolic process
B	0031012	cellular_component	extracellular matrix
B	0032288	biological_process	myelin assembly
B	0040037	biological_process	negative regulation of fibroblast growth factor receptor signaling pathway
B	0043202	cellular_component	lysosomal lumen
B	0043236	molecular_function	laminin binding
B	0045121	cellular_component	membrane raft
B	0045202	cellular_component	synapse
B	0062023	cellular_component	obsolete collagen-containing extracellular matrix
B	0070062	cellular_component	extracellular exosome
B	0098552	cellular_component	side of membrane
B	1905475	biological_process	regulation of protein localization to membrane
B	2001016	biological_process	positive regulation of skeletal muscle cell differentiation
C	0005507	molecular_function	copper ion binding
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005654	cellular_component	nucleoplasm
C	0005768	cellular_component	endosome
C	0005796	cellular_component	Golgi lumen
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0009966	biological_process	regulation of signal transduction
C	0009986	cellular_component	cell surface
C	0014037	biological_process	Schwann cell differentiation
C	0016477	biological_process	cell migration
C	0017134	molecular_function	fibroblast growth factor binding
C	0030200	biological_process	heparan sulfate proteoglycan catabolic process
C	0031012	cellular_component	extracellular matrix
C	0032288	biological_process	myelin assembly
C	0040037	biological_process	negative regulation of fibroblast growth factor receptor signaling pathway
C	0043202	cellular_component	lysosomal lumen
C	0043236	molecular_function	laminin binding
C	0045121	cellular_component	membrane raft
C	0045202	cellular_component	synapse
C	0062023	cellular_component	obsolete collagen-containing extracellular matrix
C	0070062	cellular_component	extracellular exosome
C	0098552	cellular_component	side of membrane
C	1905475	biological_process	regulation of protein localization to membrane
C	2001016	biological_process	positive regulation of skeletal muscle cell differentiation
D	0005507	molecular_function	copper ion binding
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0005654	cellular_component	nucleoplasm
D	0005768	cellular_component	endosome
D	0005796	cellular_component	Golgi lumen
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0009966	biological_process	regulation of signal transduction
D	0009986	cellular_component	cell surface
D	0014037	biological_process	Schwann cell differentiation
D	0016477	biological_process	cell migration
D	0017134	molecular_function	fibroblast growth factor binding
D	0030200	biological_process	heparan sulfate proteoglycan catabolic process
D	0031012	cellular_component	extracellular matrix
D	0032288	biological_process	myelin assembly
D	0040037	biological_process	negative regulation of fibroblast growth factor receptor signaling pathway
D	0043202	cellular_component	lysosomal lumen
D	0043236	molecular_function	laminin binding
D	0045121	cellular_component	membrane raft
D	0045202	cellular_component	synapse
D	0062023	cellular_component	obsolete collagen-containing extracellular matrix
D	0070062	cellular_component	extracellular exosome
D	0098552	cellular_component	side of membrane
D	1905475	biological_process	regulation of protein localization to membrane
D	2001016	biological_process	positive regulation of skeletal muscle cell differentiation

Functional Information from PROSITE/UniProt

site_id	PS01207
Number of Residues	24
Details	GLYPICAN Glypicans signature. CahClGVpgarPCpdYCrnVlkGC

Chain	Residue	Details
A	CYS256-CYS279

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"21932778","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22351761","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"2148568","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21932778","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22351761","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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