4AD7

Crystal structure of full-length N-glycosylated human glypican-1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	GLYPICAN-1	polymer	528	58785.3	4	UniProt (P35052) Pfam (PF01153)	HOMO SAPIENS (HUMAN)	SECRETED GLYPICAN-1
2	E, F, G, H, I... (A, B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
3	K, L, M, N (A, B, C, D)	water	water		18.0	126	Chemie (HOH)

Sequence modifications

A, B, C, D: 24 - 529 (UniProt: P35052)

PDB	External Database	Details
Ala 2	-	expression tag
Pro 3	-	expression tag
Gln 4	-	expression tag
Leu 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
Asp 12	-	expression tag
Leu 13	-	expression tag
Tyr 14	-	expression tag
Glu 15	-	expression tag
Asn 16	-	expression tag
Leu 17	-	expression tag
Tyr 18	-	expression tag
Phe 19	-	expression tag
Gln 20	-	expression tag
Gly 21	-	expression tag
Lys 22	-	expression tag
Leu 23	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	235141.0
Non-Polymers*	Number of molecules	6
	Total formula weight	1327.2
All*	Total formula weight	236468.3

*Water molecules are not included.