4X41
Crystal Structure of Protein Arginine Methyltransferase PRMT8
Summary for 4X41
Entry DOI | 10.2210/pdb4x41/pdb |
Descriptor | Protein arginine N-methyltransferase 8, S-ADENOSYL-L-HOMOCYSTEINE (2 entities in total) |
Functional Keywords | protein arginine methyltransferase, methylation, dimerization, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side : Q9NR22 |
Total number of polymer chains | 2 |
Total formula weight | 83613.45 |
Authors | |
Primary citation | Lee, W.C.,Lin, W.L.,Matsui, T.,Chen, E.S.,Wei, T.Y.,Lin, W.H.,Hu, H.,Zheng, Y.G.,Tsai, M.D.,Ho, M.C. Protein Arginine Methyltransferase 8: Tetrameric Structure and Protein Substrate Specificity Biochemistry, 54:7514-7523, 2015 Cited by PubMed: 26529540DOI: 10.1021/acs.biochem.5b00995 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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