4W4O
High-resolution crystal structure of Fc bound to its human receptor Fc-gamma-RI
Summary for 4W4O
Entry DOI | 10.2210/pdb4w4o/pdb |
Related | 4W4N |
Descriptor | Ig gamma-1 chain C region, High affinity immunoglobulin gamma Fc receptor I, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | immune complex igg1 protein-protein complex asymmetry, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 87850.19 |
Authors | Caaveiro, J.M.M.,Kiyoshi, M.,Tsumoto, K. (deposition date: 2014-08-15, release date: 2015-04-29, Last modification date: 2023-11-08) |
Primary citation | Kiyoshi, M.,Caaveiro, J.M.M.,Kawai, T.,Tashiro, S.,Ide, T.,Asaoka, Y.,Hatayama, K.,Tsumoto, K. Structural basis for binding of human IgG1 to its high-affinity human receptor Fc gamma RI Nat Commun, 6:6866-6866, 2015 Cited by PubMed: 25925696DOI: 10.1038/ncomms7866 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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