4UT6

Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 B7

Summary for 4UT6

Entry DOI	10.2210/pdb4ut6/pdb
Related	4UT7 4UT8 4UT9
Descriptor	ENVELOPE GLYCOPROTEIN E, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 B7, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2, ... (6 entities in total)
Functional Keywords	viral protein, membrane fusion, class 2 fusion protein, dengue antibody neutralization, immune system, immune system-viral protein complex
Biological source	DENGUE VIRUS 2 More
Total number of polymer chains	6
Total formula weight	202422.84
Authors	Rouvinski, A.,Guardado-Calvo, P.,Barba-Spaeth, G.,Duquerroy, S.,Vaney, M.C.,Rey, F.A. (deposition date: 2014-07-18, release date: 2015-01-28, Last modification date: 2024-01-10)
Primary citation	Rouvinski, A.,Guardado-Calvo, P.,Barba-Spaeth, G.,Duquerroy, S.,Vaney, M.,Kikuti, C.M.,Sanchez, M.E.N.,Dejnirattisai, W.,Wongwiwat, W.,Haouz, A.,Girard-Blanc, C.,Petres, S.,Shepard, W.E.,Despres, P.,Arenzana-Seisdedos, F.,Dussart, P.,Mongkolsapaya, J.,Screaton, G.R.,Rey, F.A. Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses. Nature, 520:109-, 2015 Cited by PubMed: 25581790 DOI: 10.1038/NATURE14130 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation