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4UT6

Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 B7

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
ENVELOPE GLYCOPROTEIN Epolymer42246816.52Pfam (PF00869)
Pfam (PF02832)
UniProt (by SIFTS) (A0A0B4SHY9)
DENGUE VIRUS 2E PROTEIN
2C, D
(H, I)
BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 B7polymer28330161.32HOMO SAPIENS (HUMAN)
3E, F
(L, M)
BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2polymer21822955.42HOMO SAPIENS (HUMAN)
4G, H
(C, D)
alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched1057.02In PDB
GlyTouCan (G82348BZ)
5I, J
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
6K, L, M, N, O
(A, B, H, I, L)
waterwater18.026Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight199866.5
BranchedNumber of molecules2
Total formula weight2113.9
Non-Polymers*Number of molecules2
Total formula weight442.4
All*Total formula weight202422.8
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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