4RMF
Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target
Summary for 4RMF
Entry DOI | 10.2210/pdb4rmf/pdb |
Descriptor | Aspartate--tRNA(Asp/Asn) ligase, 2,2-bis(hydroxymethyl)propane-1,3-diol, FORMIC ACID, ... (4 entities in total) |
Functional Keywords | alpha and beta proteins, trna synthetase, trna, ligase |
Biological source | Mycobacterium smegmatis |
Cellular location | Cytoplasm : A0QWN3 |
Total number of polymer chains | 1 |
Total formula weight | 66711.91 |
Authors | Cox, J.A.G.,Gurcha, S.S.,Veeraraghavan, U.,Besra, G.S.,Futterer, K. (deposition date: 2014-10-21, release date: 2014-11-19, Last modification date: 2023-09-20) |
Primary citation | Gurcha, S.S.,Usha, V.,Cox, J.A.,Futterer, K.,Abrahams, K.A.,Bhatt, A.,Alderwick, L.J.,Reynolds, R.C.,Loman, N.J.,Nataraj, V.,Alemparte, C.,Barros, D.,Lloyd, A.J.,Ballell, L.,Hobrath, J.V.,Besra, G.S. Biochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target. Plos One, 9:e113568-e113568, 2014 Cited by PubMed: 25409504DOI: 10.1371/journal.pone.0113568 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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