4QIL
Crystal structure of the ROQ domain of human Roquin in complex with the Hmg19 stem-loop RNA
Summary for 4QIL
Entry DOI | 10.2210/pdb4qil/pdb |
Related | 4QIK |
Descriptor | Roquin-1, 5'-R(*CP*UP*CP*CP*CP*UP*UP*CP*UP*GP*UP*GP*AP*AP*GP*GP*GP*GP*A)-3', CALCIUM ION, ... (4 entities in total) |
Functional Keywords | winged-helix motif, mrna stem-loop, mrna decay, immune responses, autoimmunity, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, P-body (By similarity): Q5TC82 |
Total number of polymer chains | 4 |
Total formula weight | 86650.29 |
Authors | |
Primary citation | Tan, D.,Zhou, M.,Kiledjian, M.,Tong, L. The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA. Nat.Struct.Mol.Biol., 21:679-685, 2014 Cited by PubMed: 25026078DOI: 10.1038/nsmb.2857 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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