4QEO

crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH

Summary for 4QEO

• Entry DOI: 10.2210/pdb4qeo/pdb
• Related: 4QEN 4QEP
• Descriptor: Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH4, DNA 5'-GGTACT(5CM)ATCAGTAT-3', DNA 5'-ACTGATGAGTACCAT-3', ... (7 entities in total)
• Functional Keywords: sra, set, histone methylation, methylated dna, methylation, transcription-dna complex, transcription/dna
• Biological source: Arabidopsis thaliana (mouse-ear cress,thale-cress); More
• Cellular location: Nucleus: Q8GZB6
• Total number of polymer chains: 4
• Total formula weight: 71089.67

Authors

Du, J.,Li, S.,Patel, D.J. (deposition date: 2014-05-17, release date: 2014-07-30, Last modification date: 2024-03-13)

• Primary citation: Du, J.,Johnson, L.M.,Groth, M.,Feng, S.,Hale, C.J.,Li, S.,Vashisht, A.A.,Gallego-Bartolome, J.,Wohlschlegel, J.A.,Patel, D.J.,Jacobsen, S.E.; Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.; Mol.Cell, 55:495-504, 2014; PubMed: 25018018; DOI: 10.1016/j.molcel.2014.06.009

Experimental method

X-RAY DIFFRACTION (2 Å)