4OLF

Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase)from Plasmodium falciparum in complex with Halofuginone and AMPPNP

Summary for 4OLF

• Entry DOI: 10.2210/pdb4olf/pdb
• Related: 4NCX
• Descriptor: Proline--tRNA ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ... (7 entities in total)
• Functional Keywords: structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, prolyl-trna synthetase, ligase
• Biological source: Plasmodium falciparum
• Cellular location: Cytoplasm : Q8I5R7
• Total number of polymer chains: 1
• Total formula weight: 61433.38

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2014-01-23, release date: 2015-04-15, Last modification date: 2023-09-20)

• Primary citation: Dranow, D.M.,Edwards, T.E.,Lorimer, D.,Seattle Structural Genomics Center for Infectious Disease; Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase)from Plasmodium falciparum in complex with Halofuginone and AMPPNP; To be Published,

Experimental method

X-RAY DIFFRACTION (2.9 Å)