4NWD
Crystal structure of the kainate receptor GluK3 ligand-binding domain in complex with the agonist (2S,4R)-4-(3-Methylamino-3-oxopropyl)glutamic acid at 2.6 A resolution
Summary for 4NWD
Entry DOI | 10.2210/pdb4nwd/pdb |
Related | 3S9E 4MH5 4NWC |
Descriptor | Glutamate receptor ionotropic, kainate 3, (4R)-4-[3-(methylamino)-3-oxopropyl]-L-glutamic acid, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | kainate receptor, ligand binding domain, agonist, ionotropic glutamate receptor, membrabe protein-agonist complex, membrane protein-agonist complex, membrane protein/agonist |
Biological source | Rattus norvegicus (brown rat,rat,rats) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P42264 |
Total number of polymer chains | 1 |
Total formula weight | 29438.34 |
Authors | Venskutonyte, R.,Larsen, A.P.,Frydenvang, K.,Gajhede, M.,Kastrup, J.S. (deposition date: 2013-12-06, release date: 2014-08-06, Last modification date: 2023-09-20) |
Primary citation | Venskutonyte, R.,Larsen, A.P.,Frydenvang, K.,Gajhede, M.,Sagot, E.,Assaf, Z.,Gefflaut, T.,Pickering, D.S.,Bunch, L.,Kastrup, J.S. Molecular Recognition of Two 2,4-syn-Functionalized (S)-Glutamate Analogues by the Kainate Receptor GluK3 Ligand Binding Domain. Chemmedchem, 9:2254-2259, 2014 Cited by PubMed: 25044437DOI: 10.1002/cmdc.201402204 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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