4NWD

Crystal structure of the kainate receptor GluK3 ligand-binding domain in complex with the agonist (2S,4R)-4-(3-Methylamino-3-oxopropyl)glutamic acid at 2.6 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE 2QD A 301

Chain	Residue
A	GLU15
A	ASN174
A	GLU191
A	THR194
A	TYR217
A	TYR63
A	PRO90
A	LEU91
A	THR92
A	ARG97
A	GLY142
A	ALA143
A	THR144

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE K A 302

Chain	Residue
A	SER24
A	ARG26

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K A 303

Chain	Residue
A	ASN5
A	ASN5
A	SER52
A	SER52
A	HOH405
A	HOH405

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 304

Chain	Residue
A	ARG33
A	ARG56
A	LEU57

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:21907808, ECO:0007744|PDB:3S9E

Chain	Residue	Details
A	PRO90
A	THR92
A	ARG97
A	ALA143
A	THR144
A	GLU191

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN5
A	ASN204

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