4NWD
Crystal structure of the kainate receptor GluK3 ligand-binding domain in complex with the agonist (2S,4R)-4-(3-Methylamino-3-oxopropyl)glutamic acid at 2.6 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutamate receptor ionotropic, kainate 3 | polymer | 258 | 29092.5 | 1 | UniProt (P42264) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (brown rat rat rats) | GluK3, Glutamate receptor 7, GluR-7, GluR7 |
| 2 | B (A) | (4R)-4-[3-(methylamino)-3-oxopropyl]-L-glutamic acid | non-polymer | 232.2 | 1 | Chemie (2QD) | |||
| 3 | C, D (A) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 4 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | F (A) | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
A: 4 - 118 (UniProt: P42264)
A: 121 - 258 (UniProt: P42264)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Pro 2 | - | expression tag |
| Gly 3 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 119 | - | linker |
| Thr 120 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29092.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 345.9 | |
| All* | Total formula weight | 29438.3 |
