4NTW

Structure of acid-sensing ion channel in complex with snake toxin

Summary for 4NTW

Entry DOI	10.2210/pdb4ntw/pdb
Related	2QTS 3HGC 4FZ0 4NTX 4NTY 4NYK
Descriptor	Acid-sensing ion channel 1, Neurotoxin MitTx-alpha, Basic phospholipase A2 homolog Tx-beta, ... (8 entities in total)
Functional Keywords	kunitz, phospholipase a2-like, ion channel, nociception, membrane, transport protein-toxin complex, transport protein/toxin
Biological source	Gallus gallus (bantam,chickens) More
Total number of polymer chains	3
Total formula weight	73042.14
Authors	Baconguis, I.,Bohlen, C.J.,Goehring, A.,Julius, D.,Gouaux, E. (deposition date: 2013-12-02, release date: 2014-02-19, Last modification date: 2020-07-29)
Primary citation	Baconguis, I.,Bohlen, C.J.,Goehring, A.,Julius, D.,Gouaux, E. X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel. Cell(Cambridge,Mass.), 156:717-729, 2014 Cited by PubMed: 24507937 DOI: 10.1016/j.cell.2014.01.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.07 Å)

Structure validation