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4NTW

Structure of acid-sensing ion channel in complex with snake toxin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Acid-sensing ion channel 1polymer45051327.41UniProt (Q1XA76)
Pfam (PF00858)
Gallus gallus (bantam chickens)ASIC1, Amiloride-sensitive cation channel 2, neuronal
2B
(B)
Neurotoxin MitTx-alphapolymer607118.01UniProt (G9I929)
Pfam (PF00014)
Micrurus tener tener (Texas coral snake)
3C
(C)
Basic phospholipase A2 homolog Tx-betapolymer11913767.61UniProt (G9I930)
Pfam (PF00068)
Micrurus tener tener (Texas coral snake)svPLA2 homolog, MitTx-beta
4D, E
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
5F
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6G, H, J
(A, C)
SODIUM IONnon-polymer23.03Chemie (NA)
7I
(A)
HEXAETHYLENE GLYCOLnon-polymer282.31Chemie (P6G)
8K, L, M
(A, B, C)
waterwater18.0323Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight72213.0
Non-Polymers*Number of molecules7
Total formula weight829.2
All*Total formula weight73042.1
*Water molecules are not included.

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PDB entries from 2025-12-03

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