4L6T
GM1 bound form of the ECX AB5 holotoxin
Summary for 4L6T
Entry DOI | 10.2210/pdb4l6t/pdb |
Related | 2wv6 4L63 |
Descriptor | ECXA, ECXB, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | cholera-like toxin, matrix metalloproteinase, bacterial mmp, metzincin, ab5, ob fold, transferase, toxin, protease, pentasacharide, gm1, ganglioside, oligosaccharide complex, toxilysin, hydrolase |
Biological source | Escherichia coli More |
Total number of polymer chains | 6 |
Total formula weight | 98430.05 |
Authors | Littler, D.R.,Ng, N.M.,Rossjohn, J.,Beddoe, T. (deposition date: 2013-06-12, release date: 2013-11-06, Last modification date: 2023-09-20) |
Primary citation | Ng, N.M.,Littler, D.R.,Paton, A.W.,Le Nours, J.,Rossjohn, J.,Paton, J.C.,Beddoe, T. EcxAB Is a Founding Member of a New Family of Metalloprotease AB5 Toxins with a Hybrid Cholera-like B Subunit. Structure, 21:2003-2013, 2013 Cited by PubMed: 24095060DOI: 10.1016/j.str.2013.08.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.859 Å) |
Structure validation
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