4KU7
Structures of PKGI Reveal a cGMP-Selective Activation Mechanism
Summary for 4KU7
Entry DOI | 10.2210/pdb4ku7/pdb |
Related | 4KU8 |
Descriptor | cGMP-dependent protein kinase 1, IODIDE ION, CYCLIC GUANOSINE MONOPHOSPHATE, ... (4 entities in total) |
Functional Keywords | cyclic nucleotide binding domain, cgmp, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q13976 |
Total number of polymer chains | 1 |
Total formula weight | 20336.72 |
Authors | Huang, G.Y.,Kim, J.J.,Reger, A.S.,Lorenz, R.,Moon, E.W.,Casteel, D.E.,Sankaran, B.,Herberg, F.W.,Kim, C. (deposition date: 2013-05-21, release date: 2014-01-15, Last modification date: 2024-02-28) |
Primary citation | Huang, G.Y.,Kim, J.J.,Reger, A.S.,Lorenz, R.,Moon, E.W.,Zhao, C.,Casteel, D.E.,Bertinetti, D.,Vanschouwen, B.,Selvaratnam, R.,Pflugrath, J.W.,Sankaran, B.,Melacini, G.,Herberg, F.W.,Kim, C. Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I. Structure, 22:116-124, 2014 Cited by PubMed: 24239458DOI: 10.1016/j.str.2013.09.021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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