4KU7
Structures of PKGI Reveal a cGMP-Selective Activation Mechanism
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cGMP-dependent protein kinase 1 | polymer | 153 | 16945.8 | 1 | UniProt (Q13976) Pfam (PF00027) | Homo sapiens (human) | cGK 1, cGK1, cGMP-dependent protein kinase I, cGKI |
| 2 | B, C, D, E, F... (A) | IODIDE ION | non-polymer | 126.9 | 24 | Chemie (IOD) | |||
| 3 | Z (A) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 1 | Chemie (PCG) | |||
| 4 | AA (A) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A: 219 - 369 (UniProt: Q13976)
| PDB | External Database | Details |
|---|---|---|
| Gly 217 | - | expression tag |
| Ser 218 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16945.8 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 3390.9 | |
| All* | Total formula weight | 20336.7 |
