4KSD
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Summary for 4KSD
Entry DOI | 10.2210/pdb4ksd/pdb |
Related | 4KSB 4KSC 4LSG |
Descriptor | Multidrug resistance protein 1A, R2 protein (2 entities in total) |
Functional Keywords | transporter, atp binding, membrane, membrane protein, transport protein |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 155687.16 |
Authors | Ward, A.,Szewczyk, P.,Grimard, V.,Lee, C.-W.,Martinez, L.,Doshi, R.,Caya, A.,Villaluz, M.,Pardon, E.,Cregger, C.,Swartz, D.J.,Falson, P.,Urbatsch, I.,Govaerts, C.,Steyaert, J.,Chang, G. (deposition date: 2013-05-17, release date: 2013-07-31, Last modification date: 2019-07-17) |
Primary citation | Ward, A.B.,Szewczyk, P.,Grimard, V.,Lee, C.W.,Martinez, L.,Doshi, R.,Caya, A.,Villaluz, M.,Pardon, E.,Cregger, C.,Swartz, D.J.,Falson, P.G.,Urbatsch, I.L.,Govaerts, C.,Steyaert, J.,Chang, G. Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain. Proc.Natl.Acad.Sci.USA, 110:13386-13391, 2013 Cited by PubMed: 23901103DOI: 10.1073/pnas.1309275110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.1001 Å) |
Structure validation
Download full validation report