4KSD
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Multidrug resistance protein 1A | polymer | 1284 | 141877.9 | 1 | UniProt (P21447) Pfam (PF00664) Pfam (PF00005) In PDB | Mus musculus (mouse) | ATP-binding cassette sub-family B member 1A, MDR1A, Multidrug resistance protein 3, P-glycoprotein 3 |
2 | B | R2 protein | polymer | 124 | 13809.3 | 1 | Lama glama (Llama) |
Sequence modifications
A: 1 - 1276 (UniProt: P21447)
PDB | External Database | Details |
---|---|---|
Leu 1277 | - | EXPRESSION TAG |
Glu 1278 | - | EXPRESSION TAG |
His 1279 | - | EXPRESSION TAG |
His 1280 | - | EXPRESSION TAG |
His 1281 | - | EXPRESSION TAG |
His 1282 | - | EXPRESSION TAG |
His 1283 | - | EXPRESSION TAG |
His 1284 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 155687.2 | |
All* | Total formula weight | 155687.2 |