4KSD

Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Multidrug resistance protein 1A	polymer	1284	141877.9	1	UniProt (P21447) Pfam (PF00664) Pfam (PF00005) In PDB	Mus musculus (mouse)	ATP-binding cassette sub-family B member 1A, MDR1A, Multidrug resistance protein 3, P-glycoprotein 3
2	B	R2 protein	polymer	124	13809.3	1		Lama glama (Llama)

Sequence modifications

A: 1 - 1276 (UniProt: P21447)

PDB	External Database	Details
Leu 1277	-	EXPRESSION TAG
Glu 1278	-	EXPRESSION TAG
His 1279	-	EXPRESSION TAG
His 1280	-	EXPRESSION TAG
His 1281	-	EXPRESSION TAG
His 1282	-	EXPRESSION TAG
His 1283	-	EXPRESSION TAG
His 1284	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	155687.2
All*	Total formula weight	155687.2

*Water molecules are not included.