4KSC
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Summary for 4KSC
Entry DOI | 10.2210/pdb4ksc/pdb |
Related | 4KSB 4KSD 4LSG |
Descriptor | Multidrug resistance protein 1A (1 entity in total) |
Functional Keywords | transporter, atp binding, membrane, membrane protein, transport protein |
Biological source | Mus musculus (mouse) |
Total number of polymer chains | 1 |
Total formula weight | 141877.88 |
Authors | Ward, A.,Szewczyk, P.,Grimard, V.,Lee, C.-W.,Martinez, L.,Doshi, R.,Caya, A.,Villaluz, M.,Pardon, E.,Cregger, C.,Swartz, D.J.,Falson, P.,Urbatsch, I.,Govaerts, C.,Steyaert, J.,Chang, G. (deposition date: 2013-05-17, release date: 2013-07-31, Last modification date: 2024-02-28) |
Primary citation | Ward, A.B.,Szewczyk, P.,Grimard, V.,Lee, C.W.,Martinez, L.,Doshi, R.,Caya, A.,Villaluz, M.,Pardon, E.,Cregger, C.,Swartz, D.J.,Falson, P.G.,Urbatsch, I.L.,Govaerts, C.,Steyaert, J.,Chang, G. Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain. Proc.Natl.Acad.Sci.USA, 110:13386-13391, 2013 Cited by PubMed: 23901103DOI: 10.1073/pnas.1309275110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4 Å) |
Structure validation
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