Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4JT6

structure of mTORDeltaN-mLST8-PI-103 complex

Summary for 4JT6
Entry DOI10.2210/pdb4jt6/pdb
Related4JSN 4JSP 4JSV 4JSX 4JT5
DescriptormTOR, mLST8, 3-(4-MORPHOLIN-4-YLPYRIDO[3',2':4,5]FURO[3,2-D]PYRIMIDIN-2-YL)PHENOL (3 entities in total)
Functional Keywordskinase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationEndoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P42345
Cytoplasm (By similarity): Q9BVC4
Total number of polymer chains4
Total formula weight341817.39
Authors
Pavletich, N.P.,Yang, H. (deposition date: 2013-03-22, release date: 2013-05-08, Last modification date: 2024-02-28)
Primary citationYang, H.,Rudge, D.G.,Koos, J.D.,Vaidialingam, B.,Yang, H.J.,Pavletich, N.P.
mTOR kinase structure, mechanism and regulation.
Nature, 497:217-223, 2013
Cited by
PubMed: 23636326
DOI: 10.1038/nature12122
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.6 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon