4JSV

mTOR kinase structure, mechanism and regulation.

Summary for 4JSV

Entry DOI	10.2210/pdb4jsv/pdb
Related	4JSN 4JSP 4JSX 4JT5
Descriptor	Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywords	kinase, transferase
Biological source	Homo sapiens (human) More
Cellular location	Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P42345 Cytoplasm (By similarity): Q9BVC4
Total number of polymer chains	4
Total formula weight	342234.90
Authors	Pavletich, N.P.,Yang, H. (deposition date: 2013-03-22, release date: 2013-05-01, Last modification date: 2024-02-28)
Primary citation	Yang, H.,Rudge, D.G.,Koos, J.D.,Vaidialingam, B.,Yang, H.J.,Pavletich, N.P. mTOR kinase structure, mechanism and regulation. Nature, 497:217-223, 2013 Cited by PubMed: 23636326 DOI: 10.1038/nature12122 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation