4JSV
mTOR kinase structure, mechanism and regulation.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (B, A) | Serine/threonine-protein kinase mTOR | polymer | 1174 | 134650.3 | 2 | UniProt (P42345) Pfam (PF02259) Pfam (PF08771) Pfam (PF00454) Pfam (PF02260) | Homo sapiens (human) | FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, mTOR, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1 |
| 2 | B, D (D, C) | Target of rapamycin complex subunit LST8 | polymer | 326 | 35910.1 | 2 | UniProt (Q9BVC4) Pfam (PF00400) | Homo sapiens (human) | TORC subunit LST8, G protein beta subunit-like, Gable, Protein GbetaL, Mammalian lethal with SEC13 protein 8, mLST8 |
| 3 | E, I (B, A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | F, G, J, K (B, A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | H, L (B, A) | TRIFLUOROMAGNESATE | non-polymer | 81.3 | 2 | Chemie (MGF) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 341120.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1114.2 | |
| All* | Total formula weight | 342234.9 |
