4JSV

mTOR kinase structure, mechanism and regulation.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	Serine/threonine-protein kinase mTOR	polymer	1174	134650.3	2	UniProt (P42345) Pfam (PF02259) Pfam (PF08771) Pfam (PF00454) Pfam (PF02260) In PDB	Homo sapiens (human)	FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, mTOR, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1
2	D, C	Target of rapamycin complex subunit LST8	polymer	326	35910.1	2	UniProt (Q9BVC4) Pfam (PF00400) In PDB	Homo sapiens (human)	TORC subunit LST8, G protein beta subunit-like, Gable, Protein GbetaL, Mammalian lethal with SEC13 protein 8, mLST8
3	B, A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
4	B, A	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	B, A	TRIFLUOROMAGNESATE	non-polymer		81.3	2	Chemie (MGF)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	341120.7
Non-Polymers*	Number of molecules	8
	Total formula weight	1114.2
All*	Total formula weight	342234.9

*Water molecules are not included.