4IUZ

High resolution crystal structure of racemic ester insulin

Summary for 4IUZ
DescriptorInsulin A chain, Insulin B chain, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywordsracemic protein crystallography, dkp ester insulin, hormone precursor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P01308 P01308
Total number of polymer chains2
Total formula weight6098.93
Authors
Avital-Shmilovici, M.,Mandal, K.,Gates, Z.P.,Phillips, N.,Weiss, M.A.,Kent, S.B.H. (deposition date: 2013-01-22, release date: 2013-02-13, Last modification date: 2013-03-20)
Primary citationAvital-Shmilovici, M.,Gates, Z.P.,Kent, S.B.,Mandal, K.,Phillips, N.B.,Weiss, M.A.
Fully Convergent Chemical Synthesis of Ester Insulin: Determination of the High Resolution X-ray Structure by Racemic Protein Crystallography.
J.Am.Chem.Soc., 135:3173-3185, 2013
PubMed: 23343390
DOI: 110.1021/ja311408y
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation
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PDB entries from 2021-06-23