4IUZ
High resolution crystal structure of racemic ester insulin
Summary for 4IUZ
Entry DOI | 10.2210/pdb4iuz/pdb |
Descriptor | Insulin A chain, Insulin B chain, DI(HYDROXYETHYL)ETHER, ... (5 entities in total) |
Functional Keywords | racemic protein crystallography, dkp ester insulin, hormone precursor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 2 |
Total formula weight | 6098.93 |
Authors | Avital-Shmilovici, M.,Mandal, K.,Gates, Z.P.,Phillips, N.,Weiss, M.A.,Kent, S.B.H. (deposition date: 2013-01-22, release date: 2013-02-13, Last modification date: 2023-09-20) |
Primary citation | Avital-Shmilovici, M.,Mandal, K.,Gates, Z.P.,Phillips, N.B.,Weiss, M.A.,Kent, S.B. Fully Convergent Chemical Synthesis of Ester Insulin: Determination of the High Resolution X-ray Structure by Racemic Protein Crystallography. J.Am.Chem.Soc., 135:3173-3185, 2013 Cited by PubMed: 23343390DOI: 10.1021/ja311408y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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