4IUZ
High resolution crystal structure of racemic ester insulin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Insulin A chain | polymer | 21 | 2383.7 | 1 | UniProt (P01308) | Homo sapiens | |
| 2 | B (B) | Insulin B chain | polymer | 30 | 3410.9 | 1 | UniProt (P01308) Pfam (PF00049) | Homo sapiens | |
| 3 | C, E (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 4 | D (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
B: 1 - 30 (UniProt: P01308)
| PDB | External Database | Details |
|---|---|---|
| Asp 10 | His 34 | engineered mutation |
| Lys 28 | Pro 52 | engineered mutation |
| Pro 29 | Lys 53 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 5794.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 304.3 | |
| All* | Total formula weight | 6098.9 |
