4I5B
Structure of human MHC class II protein HLA-DR1 carrying an influenza hemagglutinin peptide partially filling the binding groove
Summary for 4I5B
Entry DOI | 10.2210/pdb4i5b/pdb |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain, truncated hemagglutinin peptide, ... (4 entities in total) |
Functional Keywords | immunoglobulin fold, antigen presentation, peptide-mhc complex, membrane, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P01903 P04229 |
Total number of polymer chains | 6 |
Total formula weight | 90792.16 |
Authors | Schulze, M.-S.E.D. (deposition date: 2012-11-28, release date: 2013-12-04, Last modification date: 2015-04-15) |
Primary citation | Schulze, M.S.,Anders, A.K.,Sethi, D.K.,Call, M.J. Disruption of hydrogen bonds between major histocompatibility complex class II and the peptide N-terminus is not sufficient to form a human leukocyte antigen-DM receptive state of major histocompatibility complex class II. Plos One, 8:e69228-e69228, 2013 Cited by PubMed: 23976922DOI: 10.1371/journal.pone.0069228 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
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