4I5B

Structure of human MHC class II protein HLA-DR1 carrying an influenza hemagglutinin peptide partially filling the binding groove

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	HLA class II histocompatibility antigen, DR alpha chain	polymer	187	21667.5	2	UniProt (P01903) Pfam (PF00993) Pfam (PF07654)	Homo sapiens (human)	MHC class II antigen DRA
2	B, E (B, E)	HLA class II histocompatibility antigen, DRB1-1 beta chain	polymer	192	22380.9	2	UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911)	Homo sapiens (human)	MHC class II antigen DRB1*1, DR-1, DR1
3	C, F (C, F)	truncated hemagglutinin peptide	polymer	12	1347.7	2
4	G, H, I, J, K... (A, B, C, D, E...)	water	water		18.0	190	Chemie (HOH)

Sequence modifications

A, D: 2 - 188 (UniProt: P01903)

PDB	External Database	Details
Cys 65	Val 90	conflict

B, E: 2 - 193 (UniProt: P04229)

PDB	External Database	Details
Ser 30	Cys 59	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	90792.2
All*	Total formula weight	90792.2

*Water molecules are not included.