4I5B
Structure of human MHC class II protein HLA-DR1 carrying an influenza hemagglutinin peptide partially filling the binding groove
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | HLA class II histocompatibility antigen, DR alpha chain | polymer | 187 | 21667.5 | 2 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) In PDB | Homo sapiens (human) | MHC class II antigen DRA |
2 | B, E | HLA class II histocompatibility antigen, DRB1-1 beta chain | polymer | 192 | 22380.9 | 2 | UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) In PDB | Homo sapiens (human) | MHC class II antigen DRB1*1, DR-1, DR1 |
3 | C, F | truncated hemagglutinin peptide | polymer | 12 | 1347.7 | 2 | |||
4 | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A, D: 2 - 188 (UniProt: P01903)
B, E: 2 - 193 (UniProt: P04229)
PDB | External Database | Details |
---|---|---|
Cys 65 | Val 90 | CONFLICT |
PDB | External Database | Details |
---|---|---|
Ser 30 | Cys 59 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 90792.2 | |
All* | Total formula weight | 90792.2 |