4HFH

The GLIC pentameric Ligand-Gated Ion Channel (wild-type) complexed to bromoform

Summary for 4HFH

Entry DOI	10.2210/pdb4hfh/pdb
Related	4HFB 4HFC 4HFD 4HFE
Descriptor	Proton-gated ion channel, ACETATE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... (9 entities in total)
Functional Keywords	pentameric transmembrane channel, ion channel, membrane protein, transport protein
Biological source	Gloeobacter violaceus
Cellular location	Cell inner membrane; Multi-pass membrane protein (Probable): Q7NDN8
Total number of polymer chains	5
Total formula weight	194231.65
Authors	Sauguet, L.,Howard, R.J.,Malherbe, L.,Lee, U.S.,Corringer, P.J.,Harris, R.A.,Delarue, M. (deposition date: 2012-10-05, release date: 2013-04-17, Last modification date: 2024-02-28)
Primary citation	Sauguet, L.,Howard, R.J.,Malherbe, L.,Lee, U.S.,Corringer, P.J.,Harris, R.A.,Delarue, M. Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nat Commun, 4:1697-1697, 2013 Cited by PubMed: 23591864 DOI: 10.1038/ncomms2682 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation