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4HFE

The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to ethanol

Summary for 4HFE
Entry DOI10.2210/pdb4hfe/pdb
Related4HFB 4HFC 4HFD 4HFH
DescriptorProton-gated ion channel, ACETATE ION, CHLORIDE ION, ... (9 entities in total)
Functional Keywordspentameric transmembrane channel, ion-channel, membrane protein, transport protein
Biological sourceGloeobacter violaceus
Cellular locationCell inner membrane; Multi-pass membrane protein (Probable): Q7NDN8
Total number of polymer chains5
Total formula weight188463.01
Authors
Sauguet, L.,Howard, R.J.,Malherbe, L.,Lee, U.S.,Corringer, P.J.,Harris, R.A.,Delarue, M. (deposition date: 2012-10-05, release date: 2013-04-17, Last modification date: 2024-02-28)
Primary citationSauguet, L.,Howard, R.J.,Malherbe, L.,Lee, U.S.,Corringer, P.J.,Harris, R.A.,Delarue, M.
Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel.
Nat Commun, 4:1697-1697, 2013
Cited by
PubMed: 23591864
DOI: 10.1038/ncomms2682
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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