4HFE
The GLIC pentameric Ligand-Gated Ion Channel F14'A ethanol-sensitive mutant complexed to ethanol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Proton-gated ion channel | polymer | 317 | 36215.7 | 5 | UniProt (Q7NDN8) Pfam (PF02931) | Gloeobacter violaceus | GLIC, Ligand-gated ion channel, LGIC |
| 2 | BA, EA, F, KA, M... (C, A, D, B, E) | ACETATE ION | non-polymer | 59.0 | 10 | Chemie (ACT) | |||
| 3 | CA, G, H, I, NA... (C, A, D, B, E) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 4 | DA, J, K, OA, U... (C, A, D, B, E) | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 5 | GA, L, LA, MA, X (C, A, D, B) | ETHANOL | non-polymer | 46.1 | 5 | Chemie (EOH) | |||
| 6 | FA, N, O, QA, W... (C, A, D, B, E) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 6 | Chemie (LMT) | |||
| 7 | HA, P, RA, Y, ZA (C, A, D, B, E) | DIUNDECYL PHOSPHATIDYL CHOLINE | non-polymer | 622.8 | 5 | Chemie (PLC) | |||
| 8 | AA, AB, BB, IA, JA... (B, E, C, A, D) | UNKNOWN LIGAND | non-polymer | 10 | Chemie (UNL) | ||||
| 9 | CB, DB, EB, FB, GB (A, B, C, D, E) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 2 - 317 (UniProt: Q7NDN8)
| PDB | External Database | Details |
|---|---|---|
| Ala 1 | - | expression tag |
| Ala 238 | Phe 280 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 181078.3 | |
| Non-Polymers* | Number of molecules | 49 |
| Total formula weight | 7384.8 | |
| All* | Total formula weight | 188463.0 |
