4GZM

Crystal structure of RAC1 F28L mutant

Summary for 4GZM

Entry DOI	10.2210/pdb4gzm/pdb
Related	3SBD 3SBE 3TH5 4GZL
Descriptor	Ras-related C3 botulinum toxin substrate 1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION (3 entities in total)
Functional Keywords	rossmann fold, gtp binding, membrane, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity): P63000
Total number of polymer chains	2
Total formula weight	46527.15
Authors	Ha, B.H.,Boggon, T.J. (deposition date: 2012-09-06, release date: 2012-12-12, Last modification date: 2023-09-13)
Primary citation	Davis, M.J.,Ha, B.H.,Holman, E.C.,Halaban, R.,Schlessinger, J.,Boggon, T.J. RAC1P29S is a spontaneously activating cancer-associated GTPase. Proc.Natl.Acad.Sci.USA, 110:912-917, 2013 Cited by PubMed: 23284172 DOI: 10.1073/pnas.1220895110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation