4GKS

A2-MHC Complex carrying FLTGIGIITV

Summary for 4GKS

Entry DOI	10.2210/pdb4gks/pdb
Related	4GKN
Descriptor	HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, FLT Cognate peptide, ... (7 entities in total)
Functional Keywords	major histocompatibility complex, t-cell receptor, immuno, immunoglobulin, recognition, mhc, tcr, immune system
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769
Total number of polymer chains	6
Total formula weight	90815.00
Authors	Sewell, A.K.,Rizkallah, P.J.,Cole, D.K.,Wooldridge, L.,Price, D.A. (deposition date: 2012-08-13, release date: 2012-09-12, Last modification date: 2023-09-13)
Primary citation	Ekeruche-Makinde, J.,Clement, M.,Cole, D.K.,Edwards, E.S.,Ladell, K.,Miles, J.J.,Matthews, K.K.,Fuller, A.,Lloyd, K.A.,Madura, F.,Dolton, G.M.,Pentier, J.,Lissina, A.,Gostick, E.,Baxter, T.K.,Baker, B.M.,Rizkallah, P.J.,Price, D.A.,Wooldridge, L.,Sewell, A.K. T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting. J.Biol.Chem., 287:37269-37281, 2012 Cited by PubMed: 22952231 DOI: 10.1074/jbc.M112.386409 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.346 Å)

Structure validation