4FXW

Structure of phosphorylated SF1 complex with U2AF65-UHM domain

Summary for 4FXW

• Entry DOI: 10.2210/pdb4fxw/pdb
• Related: 1K1G 1OPI 2G4B 4FXX
• Descriptor: Splicing factor U2AF 65 kDa subunit, Splicing factor 1, SULFATE ION, ... (4 entities in total)
• Functional Keywords: uhm, pre-mrna splicing factor, protein binding, phosphorylation
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P26368 Q15637
• Total number of polymer chains: 4
• Total formula weight: 54041.04

Authors

Wang, W.,Bauer, W.J.,Wedekind, J.E.,Kielkopf, C.L. (deposition date: 2012-07-03, release date: 2013-01-16, Last modification date: 2017-11-15)

• Primary citation: Wang, W.,Maucuer, A.,Gupta, A.,Manceau, V.,Thickman, K.R.,Bauer, W.J.,Kennedy, S.D.,Wedekind, J.E.,Green, M.R.,Kielkopf, C.L.; Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex.; Structure, 21:197-208, 2013; PubMed: 23273425; DOI: 10.1016/j.str.2012.10.020

Experimental method

X-RAY DIFFRACTION (2.29 Å)