2G4B
Structure of U2AF65 variant with polyuridine tract
Summary for 2G4B
Entry DOI | 10.2210/pdb2g4b/pdb |
Related | 2FZR |
Descriptor | 5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', Splicing factor U2AF 65 kDa subunit, 1,4-DIETHYLENE DIOXIDE, ... (4 entities in total) |
Functional Keywords | protein-rna complex, rna splicing factor, rna recognition motif, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P26368 |
Total number of polymer chains | 2 |
Total formula weight | 21107.89 |
Authors | Sickmier, E.A.,Kielkopf, C.L. (deposition date: 2006-02-21, release date: 2006-07-25, Last modification date: 2023-08-30) |
Primary citation | Sickmier, E.A.,Frato, K.E.,Paranawithana, S.,Shen, H.,Green, M.R.,Kielkopf, C.L. Structural basis of polypyrimidine tract recognition by the essential splicing factor U2AF65. Mol.Cell, 23:49-59, 2006 Cited by PubMed: 16818232DOI: 10.1016/j.molcel.2006.05.025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report