4FXW

Structure of phosphorylated SF1 complex with U2AF65-UHM domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Splicing factor U2AF 65 kDa subunit	polymer	106	12236.4	2	UniProt (P26368) Pfam (PF00076) In PDB	Homo sapiens (human)	U2 auxiliary factor 65 kDa subunit, hU2AF(65), hU2AF65, U2 snRNP auxiliary factor large subunit
2	B, D	Splicing factor 1	polymer	124	14640.0	2	UniProt (Q15637) Pfam (PF16275) In PDB	Homo sapiens (human)	Mammalian branch point-binding protein, BBP, mBBP, Transcription factor ZFM1, Zinc finger gene in MEN1 locus, Zinc finger protein 162
3	A, B, C	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4		water	water		18.0	56	Chemie (HOH)

Sequence modifications

A, C: 375 - 475 (UniProt: P26368)

PDB	External Database	Details
Gly 370	-	EXPRESSION TAG
Pro 371	-	EXPRESSION TAG
Leu 372	-	EXPRESSION TAG
Gly 373	-	EXPRESSION TAG
Ser 374	-	EXPRESSION TAG

B, D: 14 - 132 (UniProt: Q15637)

PDB	External Database	Details
Gly 9	-	EXPRESSION TAG
Pro 10	-	EXPRESSION TAG
Leu 11	-	EXPRESSION TAG
Gly 12	-	EXPRESSION TAG
Ser 13	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	53752.8
Non-Polymers*	Number of molecules	3
	Total formula weight	288.2
All*	Total formula weight	54041.0

*Water molecules are not included.