4DVI
Crystal structure of Tankyrase 1 with IWR2
Summary for 4DVI
Entry DOI | 10.2210/pdb4dvi/pdb |
Related | 2RF5 |
Descriptor | Tankyrase-1, ZINC ION, 4-[(3aR,4S,7R,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(4-methylquinolin-8-yl)benzamide, ... (4 entities in total) |
Functional Keywords | tankyrase, parp, inhibitor, iwr2, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: O95271 |
Total number of polymer chains | 2 |
Total formula weight | 51060.41 |
Authors | Huang, X. (deposition date: 2012-02-23, release date: 2012-04-04, Last modification date: 2024-02-28) |
Primary citation | Gunaydin, H.,Gu, Y.,Huang, X. Novel binding mode of a potent and selective tankyrase inhibitor. Plos One, 7:e33740-e33740, 2012 Cited by PubMed: 22438990DOI: 10.1371/journal.pone.0033740 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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