4DVI
Crystal structure of Tankyrase 1 with IWR2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tankyrase-1 | polymer | 217 | 25041.3 | 2 | UniProt (O95271) Pfam (PF00644) | Homo sapiens (human) | TANK1, Poly [ADP-ribose] polymerase 5A, TNKS-1, TRF1-interacting ankyrin-related ADP-ribose polymerase, Tankyrase I |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | 4-[(3aR,4S,7R,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(4-methylquinolin-8-yl)benzamide | non-polymer | 423.5 | 2 | Chemie (2IW) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
A, B: 1104 - 1314 (UniProt: O95271)
| PDB | External Database | Details |
|---|---|---|
| His 1315 | - | expression tag |
| His 1316 | - | expression tag |
| His 1317 | - | expression tag |
| His 1318 | - | expression tag |
| His 1319 | - | expression tag |
| His 1320 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50082.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 977.7 | |
| All* | Total formula weight | 51060.4 |
