4DG4
Human mesotrypsin-S39Y complexed with bovine pancreatic trypsin inhibitor (BPTI)
Summary for 4DG4
Entry DOI | 10.2210/pdb4dg4/pdb |
Related | 2R9P |
Descriptor | PRSS3 protein, Pancreatic trypsin inhibitor, SULFATE ION, ... (5 entities in total) |
Functional Keywords | human mesotrypsin, canonical inhibitor, bpti, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P00974 |
Total number of polymer chains | 8 |
Total formula weight | 125790.07 |
Authors | Salameh, M.A.,Soares, A.S.,Radisky, E.S. (deposition date: 2012-01-24, release date: 2012-09-12, Last modification date: 2018-01-24) |
Primary citation | Salameh, M.A.,Soares, A.S.,Alloy, A.,Radisky, E.S. Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors. Protein Sci., 21:1103-1112, 2012 Cited by PubMed: 22610453DOI: 10.1002/pro.2097 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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