4DEP

Structure of the IL-1b signaling complex

Summary for 4DEP

Entry DOI	10.2210/pdb4dep/pdb
Descriptor	Interleukin-1 beta, Interleukin-1 receptor type 1, Interleukin-1 receptor accessory protein, ... (5 entities in total)
Functional Keywords	b-trefoil, immunoglobulin, immune system, extracellular
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	192862.82
Authors	Thomas, C.,Garcia, K.C. (deposition date: 2012-01-21, release date: 2012-03-21, Last modification date: 2020-07-29)
Primary citation	Thomas, C.,Bazan, J.F.,Garcia, K.C. Structure of the activating IL-1 receptor signaling complex. Nat.Struct.Mol.Biol., 19:455-457, 2012 Cited by PubMed: 22426547 DOI: 10.1038/nsmb.2260 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation