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3ZYX

Crystal structure of human monoamine oxidase B in complex with methylene blue and bearing the double mutation I199A-Y326A

Summary for 3ZYX
Entry DOI10.2210/pdb3zyx/pdb
Related1GOS 1H8R 1OJ9 1OJA 1OJC 1OJD 1S2Q 1S2Y 1S3B 1S3E 2BK3 2BK4 2BK5 2BYB 2C64 2C65 2C66 2C67 2C70 2C72 2C73 2C75 2C76 2V5Z 2V60 2V61 2VRL 2VRM 2VZ2 2XCG 2XFN 2XFO 2XFP 2XFQ 2XFU
DescriptorAMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, ... (4 entities in total)
Functional Keywordsoxidoreductase, inhibitor
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationMitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side: P27338
Total number of polymer chains2
Total formula weight119284.62
Authors
Milczek, E.M.,Binda, C.,Rovida, S.,Mattevi, A.,Edmondson, D.E. (deposition date: 2011-08-29, release date: 2011-12-14, Last modification date: 2023-12-20)
Primary citationMilczek, E.M.,Binda, C.,Rovida, S.,Mattevi, A.,Edmondson, D.E.
The 'Gating' Residues Ile199 and Tyr326 in Human Monoamine Oxidase B Function in Substrate and Inhibitor Recognition.
FEBS J., 278:4860-, 2011
Cited by
PubMed: 21978362
DOI: 10.1111/J.1742-4658.2011.08386.X
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

건을2024-03-27부터공개중

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