3ZUV

Crystal structure of a designed selected Ankyrin Repeat protein in complex with the phosphorylated MAP kinase ERK2

3ZUV の概要

• エントリーDOI: 10.2210/pdb3zuv/pdb
• 関連するPDBエントリー: 1ERK 1GOL 2ERK 2GPH 3ERK 3ZU7 4ERK
• 分子名称: MITOGEN-ACTIVATED PROTEIN KINASE 1, DESIGNED ANKYRIN REPEAT PROTEIN, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: de novo protein-transferase complex, ankyrin repeat protein, selected binder, protein design, de novo protein/transferase
• 由来する生物種: RATTUS NORVEGICUS (NORWAY RAT); 詳細
• 細胞内の位置: Nucleus (By similarity): P63086
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 114329.96

構造登録者

Kummer, L.,Mittl, P.R.,Pluckthun, A. (登録日: 2011-07-20, 公開日: 2012-06-27, 最終更新日: 2023-12-20)

• 主引用文献: Kummer, L.,Parizek, P.,Rube, P.,Millgramm, B.,Prinz, A.,Mittl, P.R.,Kaufholz, M.,Zimmermann, B.,Herberg, F.W.,Pluckthun, A.; Structural and Functional Analysis of Phosphorylation-Specific Binders of the Kinase Erk from Designed Ankyrin Repeat Protein Libraries.; Proc.Natl.Acad.Sci.USA, 109:E2248-, 2012; PubMed: 22843676; DOI: 10.1073/PNAS.1205399109

実験手法

X-RAY DIFFRACTION (2.72 Å)