3WPE
Crystal structure of bovine TLR9 in complex with agonistic DNA1668_12mer
Summary for 3WPE
Entry DOI | 10.2210/pdb3wpe/pdb |
Related | 3WPB 3WPC 3WPD 3WPF 3WPG 3WPH 3WPI |
Descriptor | Toll-like receptor 9, DNA (5'-D(*CP*AP*TP*GP*AP*CP*GP*TP*TP*CP*CP*T)-3') (3 entities in total) |
Functional Keywords | leucine rich repeat, receptor, innate immunity, dna binding, glycosylation, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Bos taurus (Bovine) More |
Cellular location | Endoplasmic reticulum membrane ; Single-pass type I membrane protein : Q5I2M5 |
Total number of polymer chains | 2 |
Total formula weight | 92936.90 |
Authors | Ohto, U.,Tanji, H.,Shimizu, T. (deposition date: 2014-01-11, release date: 2015-02-11, Last modification date: 2015-05-06) |
Primary citation | Ohto, U.,Shibata, T.,Tanji, H.,Ishida, H.,Krayukhina, E.,Uchiyama, S.,Miyake, K.,Shimizu, T. Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9 Nature, 520:702-705, 2015 Cited by PubMed: 25686612DOI: 10.1038/nature14138 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.38 Å) |
Structure validation
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