3WPE

Crystal structure of bovine TLR9 in complex with agonistic DNA1668_12mer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002224	biological_process	toll-like receptor signaling pathway
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00041
Number of Residues	45
Details	HTH_ARAC_FAMILY_1 Bacterial regulatory proteins, araC family signature. QLkaLSngSlppgirlqkLdVSSNSiGFvipg.FfvrATRliElNL

Chain	Residue	Details
A	GLN686-LEU730

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	23
Details	Repeat: {"description":"LRR 1"}

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site_id	SWS_FT_FI2
Number of Residues	23
Details	Repeat: {"description":"LRR 2"}

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site_id	SWS_FT_FI3
Number of Residues	25
Details	Repeat: {"description":"LRR 3"}

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site_id	SWS_FT_FI4
Number of Residues	16
Details	Repeat: {"description":"LRR 4"}

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site_id	SWS_FT_FI5
Number of Residues	23
Details	Repeat: {"description":"LRR 5"}

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site_id	SWS_FT_FI6
Number of Residues	23
Details	Repeat: {"description":"LRR 6"}

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site_id	SWS_FT_FI7
Number of Residues	19
Details	Repeat: {"description":"LRR 7"}

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site_id	SWS_FT_FI8
Number of Residues	25
Details	Repeat: {"description":"LRR 8"}

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site_id	SWS_FT_FI9
Number of Residues	23
Details	Repeat: {"description":"LRR 9"}

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site_id	SWS_FT_FI10
Number of Residues	24
Details	Repeat: {"description":"LRR 10"}

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site_id	SWS_FT_FI11
Number of Residues	23
Details	Repeat: {"description":"LRR 11"}

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site_id	SWS_FT_FI12
Number of Residues	23
Details	Repeat: {"description":"LRR 12"}

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site_id	SWS_FT_FI13
Number of Residues	23
Details	Repeat: {"description":"LRR 13"}

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site_id	SWS_FT_FI14
Number of Residues	23
Details	Repeat: {"description":"LRR 15"}

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site_id	SWS_FT_FI15
Number of Residues	23
Details	Repeat: {"description":"LRR 16"}

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site_id	SWS_FT_FI16
Number of Residues	23
Details	Repeat: {"description":"LRR 17"}

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site_id	SWS_FT_FI17
Number of Residues	27
Details	Repeat: {"description":"LRR 18"}

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site_id	SWS_FT_FI18
Number of Residues	24
Details	Repeat: {"description":"LRR 19"}

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site_id	SWS_FT_FI19
Number of Residues	22
Details	Repeat: {"description":"LRR 20"}

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site_id	SWS_FT_FI20
Number of Residues	23
Details	Repeat: {"description":"LRR 21"}

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site_id	SWS_FT_FI21
Number of Residues	23
Details	Repeat: {"description":"LRR 22"}

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site_id	SWS_FT_FI22
Number of Residues	23
Details	Repeat: {"description":"LRR 23"}

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site_id	SWS_FT_FI23
Number of Residues	22
Details	Repeat: {"description":"LRR 24"}

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site_id	SWS_FT_FI24
Number of Residues	23
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25686612","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3WPE","evidenceCode":"ECO:0007744"}]}

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Residue

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site_id	SWS_FT_FI25
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q2EEY0","evidenceCode":"ECO:0000250"}]}

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site_id	SWS_FT_FI26
Number of Residues	2
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"UniProtKB","id":"Q9NR96","evidenceCode":"ECO:0000250"}]}

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site_id	SWS_FT_FI27
Number of Residues	13
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

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